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May 29, 2025AnimalsOpen Access

Multiplex qPCR assay detects DEV, GPV, and MDPV with high sensitivity and specificity.

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Why the study?

Duck enteritis virus, goose parvovirus, and muscovy duck parvovirus cause similar symptoms such as severe diarrhea, creating a need for a rapid and precise assay to detect all three viruses.

Population

215 clinical samples

Design

Assay development and validation study

Key result

A multiplex qPCR assay was developed for detecting DEV, GPV, and MDPV with detection limits of 11.6, 95, and 14.8 copies respectively, demonstrating high sensitivity and specificity.

Authors

QQQian QiuRHRuiming HuZLZirui Liu

Discussion

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Overview

May enable multiplex screening in waterfowl research; leaves open clinical validation before diagnostic use.

Structured PICO

P
Population
215 clinical samples for the detection of Duck enteritis virus (DEV), goose parvovirus (GPV), and muscovy duck parvovirus (MDPV)
I
Intervention
TaqMan probe-based multiplex quantitative polymerase chain reaction (qPCR) assay
O
Outcome
Detection limit, sensitivity, specificity, and stability of the multiplex qPCR assaysurrogate

The developed multiplex qPCR assay provides a rapid, sensitive, and specific tool for the simultaneous detection of DEV, GPV, and MDPV in waterfowl.

Cite This Study

Qiu et al. (2025) studied Duck enteritis virus (DEV), goose parvovirus (GPV), and muscovy duck parvovirus (MDPV) infection (n=215). TaqMan probe-based multiplex qPCR assay was evaluated on Detection limit, sensitivity, specificity, and stability of the assay. A multiplex qPCR assay was developed for detecting DEV, GPV, and MDPV with detection limits of 11.6, 95, and 14.8 copies respectively, demonstrating high sensitivity and specificity.

synapsesocial.com/papers/6a0eddee53f874f2b222dea8https://doi.org/10.3390/ani15111599
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Development and application of quadruplex real time quantitative PCR method for differentiation of Muscovy duck parvovirus, Goose parvovirus, Duck circovirus, and Duck adenovirus 32024 · 6 citations
  2. 2A Multiplex TaqMan‐MGB qPCR Assay for Rapid and Accurate Identification of Four Waterfowl Parvoviruses (cGPV, MDPV, MDGPV, and SBDSV)2025
  3. 3One-Step Multiplex Real-Time Fluorescent Quantitative Reverse Transcription PCR for Simultaneous Detection of Four Waterfowl Viruses2024 · 3 citations
  4. 4Development and application of multiplex PCR method for simultaneous detection of seven viruses in ducks2019 · 38 citations
  5. 5Quantitative analysis of waterfowl parvoviruses in geese and Muscovy ducks by real-time polymerase chain reaction: correlation between age, clinical symptoms and DNA copy number of waterfowl parvoviruses2012 · 45 citations