Key result
Hypertension shows no significant link to frailty.
Why the study?
To review the association between hypertension and frailty in observational studies.
Is hypertension associated with an increased prevalence of frailty in adult persons?
Meta-Analysis (n=7,656)
Is hypertension associated with an increased prevalence of frailty in adult persons?
Effect estimate: OR 1.33 (95% CI 0.94-1.89)
Frailty is highly prevalent among individuals with hypertension, highlighting the need to assess frailty to optimize the risk-benefit ratio of antihypertensive treatment.
No takes yet. Share an insight, caveat, or question.
Non-significant hypertension-frailty association leaves relationship open; supports prospective trials on frailty assessment before guiding antihypertensive decisions.
Vetrano et al. (2018) conducted a meta-analysis in Hypertension and frailty (n=7,656). Hypertension was evaluated on Association between frailty and hypertension (OR 1.33, 95% CI 0.94-1.89). Hypertension showed a non-significant association with frailty (pooled OR 1.33; 95% CI 0.94-1.89), although the pooled prevalence of frailty in individuals with hypertension was 14%.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: