Key result
Deceased patients with ventricular tachycardia had heavier, more dilated hearts with larger, more solid infarcts and greater areas of spared subendocardium compared to controls.
Why the study?
Does the anatomic and histologic structure of myocardial infarction differ in patients with versus without ventricular tachycardia?
Population
43 deceased patients with myocardial infarction, including 22 with ventricular tachycardia and 21 control…
Design
Case-control
Authors
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Distinct post-MI substrate features associate with ventricular tachycardia; hypothesis-generating for risk stratification and ablation targets.
Case-Control (n=43)
Does the anatomic and histologic structure of myocardial infarction differ in patients with versus without ventricular tachycardia?
Patients with ventricular tachycardia post-myocardial infarction have a distinct anatomic substrate characterized by larger, more solid infarcts and greater areas of spared subendocardium compared to those without ventricular tachycardia.
Bolick et al. (1986) conducted a case-control in Myocardial infarction with ventricular tachycardia (n=43). Ventricular tachycardia vs. Control (no ventricular tachycardia) was evaluated on Myocardial infarct structure (heart weight, dilation, infarct solidity, spared subendocardium). Deceased patients with ventricular tachycardia had heavier, more dilated hearts with larger, more solid infarcts and greater areas of spared subendocardium compared to controls.
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