Key result
Resistance exercise boosts load capacity and soleus protein expression in infarcted rats without altering LV function.
Why the study?
Current guidelines recommend resistance exercise with aerobic training during cardiac remodeling, but the effects of resistance training on cardiac remodeling and soleus muscle remain unclear.
Does resistance training improve cardiac remodeling and soleus muscle function in rats with long-term myocardial infarction?
Population
Long-term myocardial infarction rats
Comparison
Resistance training vs untrained MI vs Sham
Design
Animal experimental study
Follow-up
12 weeks
Authors
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May support muscle benefits without cardiac harm in MI models; leaves open translation to human post-MI care.
Does resistance training improve cardiac remodeling and soleus muscle function in rats with long-term myocardial infarction?
In a rat model of myocardial infarction, resistance exercise safely increases muscle strength and improves soleus muscle protein turnover and antioxidant response without worsening cardiac remodeling.
Souza et al. (2023) studied Myocardial infarction (in rats). Resistance exercise vs. Sham and untrained MI groups was evaluated on Cardiac remodeling, soleus muscle protein expression, and mortality. Resistance exercise increased maximal load capacity and improved soleus muscle protein expression without changing cardiac structure or left ventricular function in infarcted rats.
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