Key result
Preoperative coronary angiography fails to reduce 30-day mortality in patients undergoing CIED explantation for infection.
Why the study?
The role of routine coronary angiography as part of preoperative evaluation before infection-related cardiac implantable electronic device explantation remains uncertain.
Does preoperative coronary angiography improve 30-day mortality and perioperative complications in patients undergoing CIED explantation for infection?
Cohort (n=287)
No
Does preoperative coronary angiography improve 30-day mortality and perioperative complications in patients undergoing CIED explantation for infection?
Absolute Event Rate: 9.2% vs 9.6%
p-value: p=1.00
Routine preoperative coronary angiography before CIED explantation due to infection does not significantly influence 30-day mortality or short-term outcomes, suggesting it may be safely omitted in selected patients.
May support omitting routine preoperative angiography before CIED explantation for infection in selected patients; leaves open need for randomized confirmation.
Background: Device-associated endocarditis is a potentially life-threatening condition that typically requires the removal of the cardiac implantable electronic device (CIED). The role of routine coronary angiography (CAG) as part of preoperative evaluation remains uncertain. Objectives: This study aims to assess the necessity of preoperative CAG and its impact on clinical outcomes in patients who underwent isolated CIED explantation due to infection. Methods: A single-center retrospective analysis was conducted at Jena University Hospital between 2007 and 2023. The primary outcome was 30-day mortality. The secondary outcomes were major perioperative complications. The data were displayed using descriptive statistics and classic 2-sided tests. Conclusions: The analysis suggests that preoperative CAG does not significantly influence short-term outcomes after CIED explantation due to infection in our patient population. Systematic preoperative CAG may not be necessary for all patients. Moreover, non-invasive imaging modalities may have emerging importance in scenarios like this.
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Caldonazo et al. (2026) conducted a cohort in Cardiac implantable electronic device (CIED) infection (n=287). Preoperative coronary angiography (CAG) vs. No preoperative coronary angiography was evaluated on 30-day mortality (p=1.00). Preoperative coronary angiography did not significantly influence 30-day mortality (9.2% vs 9.6%, p=1.00) compared to no angiography in patients undergoing CIED explantation due to infection.
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