Key result
Endo-epicardial ablation plus ICD prevents sustained VT recurrence at one year in a Chagas cardiomyopathy case.
Why the study?
Cardiac manifestations of Chagas' disease occur in 20%-30% of patients, presenting diagnostic and management challenges in low prevalence settings.
Case Report (n=1)
No
Highlights the importance of screening for Chagas' cardiomyopathy in immigrants from endemic regions presenting with unexplained ventricular tachycardia.
Hypothesis-generating for combined ablation plus ICD in Chagas cardiomyopathy VT; prospective trials needed before broader adoption.
Approximately 300,000 people in the United States are estimated to have Chagas' disease, with cardiac manifestations including arrhythmias occurring in 20%-30% of patients. We report a patient diagnosed with Chagas' cardiomyopathy after presenting in ventricular tachycardia. This patient was asymptomatic before her presentation with recurrent episodes of ventricular tachycardia, which motivated us to screen her since she was an immigrant from an endemic Chagas region. This manuscript highlights some of the characteristic cardiac magnetic resonance imaging (MRI) and electrophysiology findings present in patients with Chagas' cardiomyopathy. We also detail the management of patients with Chagas' cardiomyopathy who have suffered from ventricular tachycardia.
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Amin et al. (2022) conducted a case report in Chagas' cardiomyopathy with ventricular tachycardia (n=1). Endocardial and epicardial radiofrequency ablation, ICD placement, and benznidazole was evaluated on Recurrence of sustained ventricular tachycardia. Endocardial and epicardial radiofrequency ablation, along with ICD placement and medical therapy, successfully prevented recurrence of sustained ventricular tachycardia over one year of follow-up in a patient with Chagas' cardiomyopathy.
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