Key result
His-bundle pacing from the tricuspid leaflet required higher stimulus intensity than aortic root pacing (16 vs 6 mA, P<0.05) but prevented blood pressure depression seen with right ventricular pacing.
Why the study?
Does His-bundle pacing preserve hemodynamics compared to right ventricular apical pacing in a canine model?
Does His-bundle pacing preserve hemodynamics compared to right ventricular apical pacing in a canine model?
p-value: p=<0.05
His-bundle pacing preserves normal hemodynamics compared to right ventricular apical pacing in a canine model.
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May preserve hemodynamics versus right ventricular pacing in canines; leaves open translation to human His-bundle pacing.
Mabo et al. (1995) studied this question. His-bundle recording and pacing (A-H pacing) via deflectable tip multipolar catheter vs. Right ventricular apex pacing (A-RV pacing) and aortic root pacing was evaluated on Stimulus intensity for consistent His-bundle pacing and mean blood pressure (p=<0.05). His-bundle pacing from the tricuspid leaflet required higher stimulus intensity than aortic root pacing (16 vs 6 mA, P<0.05) but prevented blood pressure depression seen with right ventricular pacing.
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