Key result
LVOT PVC ablation is linked to a ~39% higher local activation index versus RVOT PVCs.
Why the study?
The study investigated local activation time (LAT) and local activation index as a new parameter during ablation of premature ventricular complexes (PVCs) arising from the right versus left ventricular outflow tract.
Do local activation time and local activation index differ between premature ventricular complexes originating from the LVOT versus the RVOT during ablation?
Cohort (n=90)
Do local activation time and local activation index differ between premature ventricular complexes originating from the LVOT versus the RVOT during ablation?
LVOT premature ventricular complexes exhibit more negative local activation time values and a higher local activation index compared to RVOT PVCs, providing useful electrophysiological parameters for ablation.
Answers are grounded in this paper and cite their sources.
May aid PVC origin differentiation during mapping; hypothesis-generating for ablation optimization pending prospective validation.
Objectives:We aim to investigate the local activation time (LAT) and local activation index as a new parameter in ablation of premature ventricular complexes (PVCs) arising from right and left ventricular outflow tract.Materials and Methods:The data of 90 patients who underwent successful ablation of PVCs originating from the right ventricular outflow tract (RVOT) and the left ventricular outflow tract (LVOT) between 2017 and 2019 were retrospectively reviewed. The clinical and demographic characteristics and electrophysiological parameters of the patients were compared. Clinical PVC LAT, catheter-induced PVC LAT and local activation index (clinical PVC LAT/catheter-induced PVC LAT), measured during ablation were compared between the groups.Results:A total of 90 patients, 45 of whom were in the RVOT and LVOT groups, were included in the study. The mean age was 43.1±14.9 years. There was no difference between the two groups in terms of age, gender, daily PVC burden, ejection fraction, procedure duration, and catheter-induced PVC LAT values. There was a significant difference between the two groups in terms of PVC QRS duration, clinical PVC LAT, and local activation index. Clinical PVC LAT was 30.9±3.4 m/sec in the RVOT group and 40.02±4.6msn in the LVOT group (p<0.0001). The local activation index was 0.97±0.05 in the RVOT group and 1.35±0.16 in the LVOT group (p<0.0001).Conclusion:LVOT PCVs had more negative LAT values and higher local activation index than RVOT PVCs in ablation procedure.
No takes yet. Share an insight, caveat, or question.
Veysel Kutay (2020) conducted a cohort in Premature ventricular complexes (PVCs) (n=90). Ablation of LVOT PVCs vs. Ablation of RVOT PVCs was evaluated on Local activation index (p=<0.0001). Ablation of LVOT PVCs demonstrated a significantly higher local activation index (1.35 vs 0.97) and more negative clinical LAT values compared to RVOT PVCs (p<0.0001).
Synapse has enriched 10 related papers. Consider them for comparative context: