December 1, 1997Journal of the American Geriatrics Society
Mortality over Four Years in SHEP Participants with a Low Ankle‐Arm Index
Key result
A low ankle-arm index (≤0.9) predicted a two- to three-fold increase in total mortality among older adults with systolic hypertension without baseline clinical CVD (RR 3.00 in men, 2.67 in women).
Why the study?
Does a low ankle-arm index predict increased total and cardiovascular mortality in older adults with systolic hypertension?
Population
1537 older adults with systolic hypertension
Comparison
Low ankle-arm index indicating subclinical… vs Normal ankle-arm index
Design
Cohort
Follow-up
4 years
Authors
Discussion
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Member takes
Implication
May aid risk stratification in systolic hypertension; extends prognostic marker data but leaves open whether screening improves outcomes.
Study Design
Type
Observational (n=1,537)
Structured PICO
Does a low ankle-arm index predict increased total and cardiovascular mortality in older adults with systolic hypertension?
P
Population
1537 older adults with systolic hypertension (subgroup of the Systolic Hypertension in the Elderly Program [SHEP])
I
Intervention
Low ankle-arm index (AAI ≤ 0.9) indicating subclinical peripheral arterial disease
C
Comparator
Normal ankle-arm index
O
Outcome
Total and cardiovascular mortality at 4 yearshard clinical
Main Result
Effect estimate: RR 3.00 (men), RR 2.67 (women)
A low ankle-arm index (≤ 0.9) is a strong predictor of total and cardiovascular mortality in older adults with systolic hypertension, suggesting its utility in risk stratification.
Cite This Study
Newman et al. (1997) conducted an observational in Systolic hypertension (n=1,537). Low ankle-arm index (AAI ≤ 0.9) vs. Normal AAI was evaluated on Total and cardiovascular mortality (RR 3.00 (men), RR 2.67 (women)). A low ankle-arm index (≤0.9) predicted a two- to three-fold increase in total mortality among older adults with systolic hypertension without baseline clinical CVD (RR 3.00 in men, 2.67 in women).