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March 1, 1991HeartOpen Access

Effect of early programmes of high and low intensity exercise on physical performance after transmural acute myocardial infarction.

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Key result

Eight weeks of group aerobic exercise training produced a small, temporarily greater physical working capacity compared to light exercise (10.8 vs 9.9 METs), with no difference at 12 months.

Why the study?

Does eight weeks of group aerobic exercise training improve physical working capacity more than group light exercise in men after transmural acute myocardial infarction?

Population

308 men with transmural (Q wave) acute myocardial infarction, admitted to a single coronary care unit

Comparison

Eight weeks of group aerobic exercise training vs Eight weeks of group light exercise

Design

RCT, randomly allocated

Follow-up

12 months

Authors

AGAlan J. GobleAustralian Centre for Heart HealthDHDavid L. HareHeart Failure & TransplantPMPeter S. MacdonaldHeart Failure & Transplant

Discussion

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Overview

Offers no sustained advantage over light exercise post-MI; challenges assumptions of lasting benefit from brief aerobic programs.

Key Points

  • To determine whether an early light exercise training program produces similar improvements in treadmill performance compared to aerobic exercise training following acute transmural myocardial infarction.
  • Randomized trial of 308 men admitted to a single coronary care unit with transmural (Q-wave) acute myocardial infarction, allocated to 8 weeks of group aerobic exercise or group light exercise.
  • Physical working capacity in metabolic equivalents (METs) was measured via treadmill testing at baseline (week 3 post-infarction), end of intervention (week 11 post-infarction), and at 12-month follow-up.
  • Physical working capacity at week 11 was 10.8 (2.3) METs in the aerobic group versus 9.9 (2.4) METs in the light exercise group, reflecting a significant difference of 0.9 METs.
  • Physical working capacity was 6.8 (2.2) vs 6.7 (2.5) METs at baseline and 10.8 (2.4) vs 10.7 (1.9) METs at 12-month review for aerobic versus light exercise groups, showing no significant late difference.
  • No significant differences existed between groups at any evaluation for resting or maximal heart rate, resting or maximal systolic blood pressure, or rate-pressure product.

Study Design

Type

RCT (n=308)

Multicenter

No

Structured PICO

Does eight weeks of group aerobic exercise training improve physical working capacity more than group light exercise in men after transmural acute myocardial infarction?

P
Population
308 men with transmural (Q wave) acute myocardial infarction, admitted to a single coronary care unit
I
Intervention
Eight weeks of group aerobic exercise training
C
Comparator
Eight weeks of group light exercise
O
Outcome
Physical working capacity (metabolic equivalents) determined by treadmill testing at the end of the study (11th week after infarction) and at 12 month reviewsurrogate

Main Result

Effect estimate: Difference 0.9 METs

Absolute Event Rate: 10.8% vs 9.9%

Aerobic exercise training provides only a small, temporary improvement in physical working capacity compared to light exercise in men recovering from transmural myocardial infarction.

Cite This Study

Goble et al. (1991) conducted an RCT in transmural (Q wave) acute myocardial infarction (n=308). Group aerobic exercise training vs. Group light exercise was evaluated on Physical working capacity (metabolic equivalents) at the end of the study (eleventh week after infarction) (Difference 0.9 METs). Eight weeks of group aerobic exercise training produced a small, temporarily greater physical working capacity compared to light exercise (10.8 vs 9.9 METs), with no difference at 12 months.

synapsesocial.com/papers/6a0ef32a1c5e2d2319fa229ehttps://doi.org/10.1136/hrt.65.3.126
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A CONTROLLED PROSPECTIVE STUDY OF THE EFFECT OF ENDURANCE TRAINING ON THE RECURRENCE RATE OF MYOCARDIAL INFARCTION1975 · 45 citations
  2. 2Heart Failure Complicating Acute Myocardial Infarction1972 · 158 citations
  3. 3The rate-pressure product as an index of myocardial oxygen consumption during exercise in patients with angina pectoris.1978 · 863 citations
  4. 4Exercise training in patients with severe left ventricular dysfunction. Hemodynamic and metabolic effects.1988 · 698 citations