Key result
Borderline hypertensive patients exhibited significantly altered left ventricular diastolic function, including higher late peak flow velocity (P<0.02) and lower early filling fraction (P<0.02), compared to normotensive controls.
Why the study?
Does borderline essential hypertension alter left ventricular anatomy and diastolic function compared to normotensive individuals?
Population
56 subjects, comprising 16 patients with borderline essential hypertension, 20 normotensive controls, and 20…
Comparison
Borderline essential hypertension vs Normotensive controls and patients with…
Design
Cross-sectional
Authors
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Borderline hypertension may link to early diastolic changes; hypothesis-generating and should not yet change practice.
Observational (n=56)
Does borderline essential hypertension alter left ventricular anatomy and diastolic function compared to normotensive individuals?
p-value: p=<0.02
Borderline hypertension is associated with early echocardiographic signs of left ventricular diastolic dysfunction and increased wall thickness, indicating early structural and functional changes.
Marabotti et al. (1989) conducted an observational in Borderline essential hypertension (n=56). Borderline essential hypertension vs. Normotension and established hypertension was evaluated on Left ventricular diastolic function indices (A peak, A/E ratio, EFF) (p=<0.02). Borderline hypertensive patients exhibited significantly altered left ventricular diastolic function, including higher late peak flow velocity (P<0.02) and lower early filling fraction (P<0.02), compared to normotensive controls.
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