Key result
Acute infectious myocarditis in patients with beta-thalassemia major led to acute heart failure in 23.4% and chronic heart failure in 27.6% of patients, serving as a main cause of death.
Why the study?
Does acute infectious myocarditis lead to left ventricular dysfunction and death in patients with beta-thalassemia major?
Population
94 patients with beta-thalassemia major, including 47 with acute infectious myocarditis and 47 age- and…
Comparison
Acute infectious myocarditis (exposure) vs Age- and sex-matched control subjects with…
Design
Cohort
Follow-up
5 years
Authors
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Highlights myocarditis as a major driver of heart failure and death in beta-thalassemia major; leaves open optimal prevention strategies.
Cohort (n=94)
Does acute infectious myocarditis lead to left ventricular dysfunction and death in patients with beta-thalassemia major?
In patients with beta-thalassemia major, acute infectious myocarditis is a major cause of left ventricular systolic dysfunction and death.
Kremastinos et al. (1995) conducted a cohort in Beta-thalassemia major (n=94). Acute infectious myocarditis vs. Age- and sex-matched controls without myocarditis was evaluated on Acute heart failure with left ventricular dysfunction. Acute infectious myocarditis in patients with beta-thalassemia major led to acute heart failure in 23.4% and chronic heart failure in 27.6% of patients, serving as a main cause of death.
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