Key result
The Ross procedure with oversized cryopreserved homografts led to a significant increase in pulmonary peak flow velocity from 0.87 m/s preoperatively to 1.30 m/s postoperatively (P<0.001).
Why the study?
Does the Ross procedure with cryopreserved homografts alter pulmonary and aortic peak flow velocities in patients undergoing aortic root replacement?
Population
60 patients undergoing aortic root replacement with pulmonary autograft and pulmonary root replacement with…
Comparison
Aortic root replacement with pulmonary autograft… vs Preoperative baseline.
Design
Cohort
Follow-up
1 year
Authors
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May signal early pulmonary homograft dysfunction after Ross; hypothesis-generating and requires prospective confirmation before practice change.
Cohort (n=60)
Does the Ross procedure with cryopreserved homografts alter pulmonary and aortic peak flow velocities in patients undergoing aortic root replacement?
Absolute Event Rate: 1.3% vs 0.87%
p-value: p=< 0.001
The Ross procedure results in a significant, progressive increase in pulmonary peak flow velocity during the first year despite the use of oversized cryopreserved homografts, suggesting potential early leaflet degeneration or valve rejection.
R. Moidl (1997) conducted a cohort in Aortic valve disease requiring aortic root replacement (n=60). Ross procedure with cryopreserved homografts vs. Preoperative baseline was evaluated on Pulmonary peak flow velocity (PVmax) (p=< 0.001). The Ross procedure with oversized cryopreserved homografts led to a significant increase in pulmonary peak flow velocity from 0.87 m/s preoperatively to 1.30 m/s postoperatively (P<0.001).
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