Key result
Higher mean left atrial pressure is linked to AF recurrence after PVI.
Why the study?
Does elevated left atrial pressure predict post-PVI recurrence of atrial fibrillation in patients with drug-refractory non-valvular atrial fibrillation?
Population
60 consecutive patients with drug-refractory non-valvular paroxysmal or persistent atrial fibrillation…
Comparison
Measurement of left atrial pressure immediately… vs Patients with mean left atrial pressure < 10…
Design
Cohort
Follow-up
13 ± 5 months
Authors
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Elevated pre-PVI left atrial pressure was associated with AF recurrence; hypothesis-generating for risk stratification pending prospective validation.
Observational (n=60)
No
Does elevated left atrial pressure predict post-PVI recurrence of atrial fibrillation in patients with drug-refractory non-valvular atrial fibrillation?
Absolute Event Rate: 12.2% vs 7.99%
p-value: p=<0.001
Elevated left atrial pressure measured before pulmonary vein isolation is significantly associated with post-ablation atrial fibrillation recurrence.
Iso et al. (2018) conducted an observational in Drug refractory non-valvular paroxysmal or persistent atrial fibrillation (n=60). Pulmonary vein isolation was evaluated on Mean left atrial pressure in patients with vs without AF recurrence (p=<0.001). Mean left atrial pressure was significantly higher in patients who experienced atrial fibrillation recurrence after pulmonary vein isolation compared to those who did not (12.2 vs 7.99 mmHg, P<0.001).
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