Key result
Left atrial hypertension independently predicted late atrial fibrillation recurrence in patients undergoing pulmonary vein isolation (HR 3.02; 95% CI 1.36-6.72; P=0.007).
Why the study?
The clinical role of left atrial hypertension in patients with AF and its predictive value in those undergoing pulmonary vein isolation remained unknown.
Does left atrial hypertension measured invasively during pulmonary vein isolation predict atrial fibrillation recurrence in patients with nonvalvular AF?
Population
98 consecutive patients with drug-resistant nonvalvular AF and preserved LVEF undergoing PV isolation
Comparison
Left atrial hypertension (LA mean pressure ≥15 mmHg) vs no left atrial hypertension
Design
Retrospective cohort study
Follow-up
Median 14 months
Authors
Loading...
LAH may flag higher late AF recurrence risk; hypothesis-generating for stratification and needs prospective validation.
Cohort (n=98)
No
Does left atrial hypertension measured invasively during pulmonary vein isolation predict atrial fibrillation recurrence in patients with nonvalvular AF?
Hazard Ratio: 3.02 (95% CI 1.36–6.72)
p-value: p=0.007
Invasively measured left atrial hypertension during pulmonary vein isolation is a strong independent predictor of late atrial fibrillation recurrence.
Manfrin et al. (2022) conducted a cohort in Drug-resistant nonvalvular atrial fibrillation (n=98). Left atrial hypertension (mean pressure ≥15 mmHg) vs. No left atrial hypertension was evaluated on Late atrial fibrillation recurrence (HR 3.02, 95% CI 1.36-6.72, p=0.007). Left atrial hypertension independently predicted late atrial fibrillation recurrence in patients undergoing pulmonary vein isolation (HR 3.02; 95% CI 1.36-6.72; P=0.007).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: