Key result
Left ventricular apical and septal pacing maintained regional cardiac mechanics, contractility, relaxation, and efficiency near native levels, whereas right ventricular pacing diminished them.
Why the study?
Does LV apical or septal pacing maintain cardiac mechanics and efficiency compared to RV pacing in dogs after AV nodal ablation?
RCT
randomized
Does LV apical or septal pacing maintain cardiac mechanics and efficiency compared to RV pacing in dogs after AV nodal ablation?
In a canine model, LV apical and septal pacing preserved cardiac mechanics and efficiency compared to RV pacing, suggesting potential benefits of LV pacing sites.
Authors
No takes yet. Share an insight, caveat, or question.
LV apical/septal pacing preserved mechanics versus RV in dogs; hypothesis-generating, does not support clinical practice change.
Mills et al. (2009) conducted an RCT in AV nodal ablation. LV apical and LV septal pacing vs. RV apex and RV septal pacing was evaluated on LV electric activation, mechanics, hemodynamic performance, and efficiency. Left ventricular apical and septal pacing maintained regional cardiac mechanics, contractility, relaxation, and efficiency near native levels, whereas right ventricular pacing diminished them.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: