Key result
Chronic right ventricular apical pacing causes dyssynchrony and heart failure, while alternative pacing sites have not consistently shown improved clinical outcomes.
Why the study?
Chronic right ventricular apical pacing can lead to left ventricular dysfunction and symptomatic heart failure, while alternative pacing sites have not consistently improved clinical outcomes.
Key points are not available for this paper at this time.
May warrant avoiding routine RV apical pacing when feasible; leaves open optimal alternative site selection pending higher-level trials.
Chronic right ventricular (RV) apical pacing causes electrical and mechanical dyssynchrony, which in turn can lead to left ventricular (LV) dysfunction and symptomatic heart failure (HF) in a non-negligible proportion of patients.1 Alternative pacing sites, such as the RV septum or the RV outflow tract, have not consistently shown improved clinical outcomes.2
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Marco et al. (2021) studied this question. Chronic right ventricular apical pacing causes dyssynchrony and heart failure, while alternative pacing sites have not consistently shown improved clinical outcomes.
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