Key result
The hepatitis C virus NS3 proteinase domain contains a highly conserved zinc binding site with S3N ligation that is required for structural integrity and enzyme activity.
Authors
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May guide NS3-targeted antivirals; leaves open clinical translation pending validation studies.
Francesco et al. (1996) studied Hepatitis C virus. The hepatitis C virus NS3 proteinase domain contains a highly conserved zinc binding site with S3N ligation that is required for structural integrity and enzyme activity.
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