Key result
Time-related changes in peak VO2 strongly predicted cardiovascular death or urgent heart transplantation, with event rates ranging from 51% for a >6% decrease to 14% for a >6% increase (P<0.0001).
Why the study?
Do time-related changes in cardiopulmonary exercise testing indices predict cardiovascular death or urgent heart transplantation in patients with stable chronic heart failure?
Population
231 stable chronic heart failure patients with left ventricular ejection fraction of 24 +/- 8% and peak VO2…
Design
Cohort
Follow-up
1167 +/- 562 days
Authors
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May aid serial risk stratification in stable HF; hypothesis-generating and requires prospective validation before practice change.
Cohort (n=231)
Do time-related changes in cardiopulmonary exercise testing indices predict cardiovascular death or urgent heart transplantation in patients with stable chronic heart failure?
p-value: p=< 0.0001
Time-related changes in peak VO2 provide significant prognostic value for predicting cardiovascular death or urgent heart transplantation in stable chronic heart failure patients.
Corrà et al. (2006) conducted a cohort in stable chronic heart failure (n=231). Time-related changes in peak VO2 was evaluated on Cardiovascular death or urgent heart transplantation (p=< 0.0001). Time-related changes in peak VO2 strongly predicted cardiovascular death or urgent heart transplantation, with event rates ranging from 51% for a >6% decrease to 14% for a >6% increase (P<0.0001).
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