Key result
New protocol details a prospective cohort study assessing cardiac dyssynchrony predictors and outcomes in HF.
Why the study?
Cardiac dyssynchrony is prevalent and associated with high costs and poor outcomes in heart failure, but little is known about it in developing countries.
What are the predictors and outcomes of cardiac dyssynchrony among patients with heart failure in central Tanzania?
Cohort
No
What are the predictors and outcomes of cardiac dyssynchrony among patients with heart failure in central Tanzania?
This protocol outlines a prospective study to evaluate the predictors and 6-month clinical outcomes of cardiac dyssynchrony in heart failure patients in Tanzania.
Answers are grounded in this paper and cite their sources.
Protocol for Tanzanian HF cohort; leaves open whether dyssynchrony predictors differ from high-income populations or warrant regional CRT adjustments.
INTRODUCTION: Cardiac Dyssynchrony is prevalent among patients with heart failure with high cost of care and potentially poor outcomes. Nevertheless, little is known about cardiac dyssynchrony among heart failure patients, especially in developing countries. This study aims at assessing the predictors and outcomes of cardiac dyssynchrony among heart failure patients attending the cardiology department at Benjamin Mkapa Referral Hospital in Dodoma, central Tanzania. METHODS: The study will follow a prospective longitudinal design involving participants aged 18 years and above with heart failure attending the Cardiology Department at Benjamin Mkapa Hospital. Heart failure will be identified based on Framingham's score and patients will be enrolled and followed up for six months. Baseline socio-demographic and clinical characteristics will be taken during enrollment. Outcomes of interest at six months include worsening of heart failure, readmission and death. Continuous data will be summarized as Mean (SD) or Median (IQR), and categorical data will be summarized using proportions and frequencies. Binary logistic regression will be used to determine predictors and outcomes of Cardiac Dyssynchrony among patients with heart failure.
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Bilikundi et al. (2023) conducted a cohort in Heart failure. Cardiac dyssynchrony was evaluated on Worsening of heart failure, readmission and death. This protocol describes a prospective longitudinal study to assess the predictors and 6-month outcomes of cardiac dyssynchrony among patients with heart failure in central Tanzania.
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