Left atrial remodeling and voltage-guided ablation outcome in persistent atrial fibrillation patients over 75 years of age

Figures

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  Figure 1. Flowchart of the study. Of the 574 patients admitted for initial radiofrequency ablation of persistent AF between November 2017 and February 2023, 353 (62%) met the inclusion criteria. One hundred thirty-three patients (23%) had no LA voltage mapping in sinus rhythm, and 88 (15%) were excluded from the analysis because of structural heart disease. AF = atrial fibrillation; CA = cardiac amyloidosis; DCM = dilated cardiomyopathy; HCM = hypertrophic cardiomyopathy; ICM = ischemic cardiomyopathy; LA = left atrial; VHD = valvular heart disease.

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  Figure 2. Pie charts showing the number of regional LVZs according to age. Patients <75 years of age had significantly fewer LVZs than did those >75 years of age (199 [70%] vs 22 [33%]; P < .01). We observed that 3 atrial regions with LVZ were significantly higher in patients >75 years of age (14 [21%] vs 13 [4.6%]; P < .01). In addition, 4 atrial regions with LVZ were more present at the limit of significance in patients >75 years of age (3 [4.5%] vs 2 [0.7%]; P = .05). LVZ = low-voltage zone.

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  Figure 3. Kaplan-Meier survival curves showing the cumulative AF/AT recurrence-free survival rates according to age after a single procedure. AA = atrial arrhythmia; AF = atrial fibrillation; AT = atrial tachycardia.