Ablation of atrial fibrillation in patients ≥75 years: long-term clinical outcome and safety
Why the study?
Does catheter ablation improve stable sinus rhythm in patients ≥75 years with symptomatic, drug-refractory atrial fibrillation?
Population
94 patients ≥75 years with symptomatic, drug-refractory atrial fibrillation, mean age 78 ± 2 years, 54 male.
Design
Cohort
Follow-up
mean 37 ± 20 months
Authors
Discussion
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Member takes
Implication
Supports ablation feasibility in selected elderly AF; leaves open need for RCTs on long-term efficacy.
Structured PICO
Does catheter ablation improve stable sinus rhythm in patients ≥75 years with symptomatic, drug-refractory atrial fibrillation?
P
Population
94 patients ≥75 years with symptomatic, drug-refractory atrial fibrillation (59% paroxysmal, 31% persistent, 11% long-standing persistent), mean age 78 ± 2 years, 54 male.
I
Intervention
Catheter ablation (circumferential pulmonary vein isolation, extended to ablation of complex fractionated atrial electrograms and/or linear lesions in non-responders)
O
Outcome
Stable sinus rhythm at long-term follow-up
Catheter ablation in patients ≥75 years provides favorable long-term rhythm control for paroxysmal AF, but is less effective for persistent or long-standing persistent AF, with an acceptable safety profile.
Cite This Study
Metzner et al. (2016) studied this question.