Why the study?
Heart failure is a severe clinical syndrome frequently complicated by ischemic stroke, warranting a summary of research on cardio-cerebral interactions regarding prevalence, etiology, and prognosis.
This review summarizes the pathophysiological mechanisms and recent clinical trial data regarding the bidirectional relationship between heart failure and ischemic stroke.
Alerts clinicians to bidirectional HF-stroke risks; leaves open optimal preventive strategies pending prospective trials.
Heart failure (HF) is a severe clinical syndrome accompanied by a number of comorbidities. Ischemic stroke occurs frequently in patients with HF as a complication of the disease. In the present review, we aimed to summarize the current state of research on the role of cardio-cerebral interactions in the prevalence, etiology, and prognosis of both diseases. The main pathophysiological mechanisms underlying the development of stroke in HF and vice versa are discussed. In addition, we reviewed the results of recent clinical trials investigating the prevalence and prevention of stroke in patients with HF.
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Barkhudaryan et al. (2021) studied this question.
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