Temporal resolution significantly affected strain and strain rate in cardiovascular magnetic resonance feature tracking, with 30 frames per cardiac cycle offering consistent strain assessments.
Cross-Sectional (n=21)
No
Does temporal and spatial resolution impact strain and strain rate measurements in CMR feature tracking in healthy subjects and heart failure patients?
Temporal resolution, but not spatial resolution, significantly affects strain and strain rate measurements in CMR feature tracking, with 30 frames/cardiac cycle offering consistent strain assessments.
p-value: p=<0.001-0.046
BACKGROUND: Myocardial deformation analyses using cardiovascular magnetic resonance (CMR) feature tracking (CMR-FT) have incremental value in the assessment of cardiac function beyond volumetric analyses. Since guidelines do not recommend specific imaging parameters, we aimed to define optimal spatial and temporal resolutions for CMR cine images to enable reliable post-processing. METHODS: Intra- and inter-observer reproducibility was assessed in 12 healthy subjects and 9 heart failure (HF) patients. Cine images were acquired with different temporal (20, 30, 40 and 50 frames/cardiac cycle) and spatial resolutions (high in-plane 1.5 × 1.5 mm through-plane 5 mm, standard 1.8 × 1.8 x 8mm and low 3.0 × 3.0 x 10mm). CMR-FT comprised left ventricular (LV) global and segmental longitudinal/circumferential strain (GLS/GCS) and associated systolic strain rates (SR), and right ventricular (RV) GLS. RESULTS: Temporal but not spatial resolution did impact absolute strain and SR. Maximum absolute changes between lowest and highest temporal resolution were as follows: 1.8% and 0.3%/s for LV GLS and SR, 2.5% and 0.6%/s for GCS and SR as well as 1.4% for RV GLS. Changes of strain values occurred comparing 20 and 30 frames/cardiac cycle including LV and RV GLS and GCS (p < 0.001-0.046). In contrast, SR values (LV GLS/GCS SR) changed significantly comparing all successive temporal resolutions (p < 0.001-0.013). LV strain and SR reproducibility was not affected by either temporal or spatial resolution, whilst RV strain variability decreased with augmentation of temporal resolution. CONCLUSION: Temporal but not spatial resolution significantly affects strain and SR in CMR-FT deformation analyses. Strain analyses require lower temporal resolution and 30 frames/cardiac cycle offer consistent strain assessments, whilst SR measurements gain from further increases in temporal resolution.
Backhaus et al. (Mon,) conducted a cross-sectional in Healthy and Heart Failure (n=21). Varying temporal and spatial resolutions in CMR-FT vs. Lowest temporal resolution (20 frames/cardiac cycle) was evaluated on Change in strain values (LV and RV GLS and GCS) comparing 20 and 30 frames/cardiac cycle (p=<0.001-0.046). Temporal resolution significantly affected strain and strain rate in cardiovascular magnetic resonance feature tracking, with 30 frames per cardiac cycle offering consistent strain assessments.
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