Key result
Molecular SPECT and PET imaging evaluate critical post-infarction remodeling processes like inflammation and angiogenesis.
Why the study?
Molecular imaging using biologically targeted markers is expanding to provide insight into pathobiological processes at molecular and cellular levels for cardiovascular disease evaluation and individualized therapy.
Molecular imaging with SPECT and PET offers targeted evaluation of critical biological processes in post-infarction cardiac remodeling, potentially guiding individualized therapy.
The role of molecular imaging technologies in detecting, evaluating, and monitoring cardiovascular disease and their treatment is expanding rapidly. Gradually replacing the conventional anatomical or physiological approaches, molecular imaging strategies using biologically targeted markers provide unique insight into pathobiological processes at molecular and cellular levels and allow for cardiovascular disease evaluation and individualized therapy. This review paper will discuss currently available and developing molecular-based single-photon emission computed tomography (SPECT) and positron emission tomography (PET) imaging strategies to evaluate post-infarction cardiac remodeling. These approaches include potential targeted methods of evaluating critical biological processes, such as inflammation, angiogenesis, and scar formation.
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Varasteh et al. (2022) conducted a review in Post-infarction cardiac remodeling. Molecular-based SPECT and PET imaging was evaluated. Molecular-based SPECT and PET imaging strategies provide targeted methods to evaluate critical biological processes in post-infarction cardiac remodeling, such as inflammation and angiogenesis.
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