This review highlights that women with chest pain should be thoroughly investigated for CAD before diagnosing NCCP, which is most commonly caused by GERD and initially managed with proton pump inhibitors.
Answers are grounded in this paper and cite their sources.
CAD exclusion essential before attributing chest pain to NCCP in women; leaves open prospective validation of GERD-first algorithms.
Noncardiac chest pain (NCCP) is very prevalent in the community. Although mortality remains low, morbidity and the financial implications are high. Women, especially those of middle age, should be thoroughly investigated as per current guidelines for coronary artery disease before labeling their chest pain as NCCP. Gastroesophageal reflux disease is the most common cause of NCCP; however other esophageal pathology including esophageal hypersensitivity, neuromuscular disease and eosinophilic esophagitis may also cause NCCP. Proton pump inhibitors are commonly used initially to manage NCCP, although patients who do not respond to this therapy require further investigation and differing treatment regimes. This article will focus on current knowledge regarding GI tract-related NCCP management strategies.
No takes yet. Share an insight, caveat, or question.
Gill et al. (2012) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: