This review highlights the pathophysiology and current treatment options for non-cardiac chest pain, a common clinical problem often related to gastroesophageal reflux, esophageal dysmotility, and visceral hypersensitivity.
May inform differential diagnosis of chest pain; leaves open comparative effectiveness of esophageal therapies.
Non-cardiac chest pain (NCCP) is a common clinical problem however the pathophysiology remains poorly understood. Until the pathophysiology is more clearly understood, certain patients with NCCP continue to experience chest pain and seek frequent medical attention. This mini-review will discuss the underlying pathophysiology of NCCP including gastrooesophageal reflux, oesophageal dysmotility and visceral hypersensitivity. Furthermore, it aims to highlight the current treatment options based on the current literature.
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James Pearson (2016) studied this question.
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