Key result
Heart-related persistent physical symptoms in NCCP are linked to ~5-fold higher odds of clinical depression.
Why the study?
Some cases of Non-Cardiac Chest Pain meet criteria for Persistent Physical Symptoms, but the psychological distress and workability in this subgroup are not well characterized.
Do NCCP patients who meet PPS criteria differ from those who do not in terms of psychological distress and workability?
Cross-Sectional (n=285)
No
Do NCCP patients who meet PPS criteria differ from those who do not in terms of psychological distress and workability?
A significant proportion of non-cardiac chest pain patients meet criteria for persistent physical symptoms, exhibiting higher psychological distress and disability, highlighting the need for targeted psychological interventions.
Answers are grounded in this paper and cite their sources.
NCCP patients meeting PPS criteria show greater distress and work impairment; observational data leaves open whether targeted interventions improve outcomes.
Non-Cardiac Chest Pain (NCCP) is persistent chest pain in the absence of identifiable cardiac pathology. Some NCCP cases meet criteria for Persistent Physical Symptoms (PPS), where the symptoms are both persistent and distressing/disabling. This study aimed to identify patients that might need specialist treatment for PPS by examining cases of NCCP that meet PPS criteria. We analysed data from 285 chest pain patients that had received an NCCP diagnosis after attending an emergency cardiac department. We compared NCCP patients who did and did not meet the additional criteria for heart-related PPS and hypothesised that the groups would differ in terms of psychological variables and workability. We determined that NCCP patients who meet PPS criteria were more likely than other NCCP patients to be inactive or unable to work, reported more general anxiety and anxiety about their health, were more depressed, ruminated more, and, importantly, had a higher number of other PPS. A high proportion of NCCP patients meet PPS criteria, and they are similar to other PPS patients in terms of comorbidity and disability. This highlights the importance of focusing psychological interventions for this subgroup on the interplay between the range of physical and psychological symptoms present.
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Flóvenz et al. (2023) conducted a cross-sectional in Non-Cardiac Chest Pain (NCCP) (n=285). Heart-related Persistent Physical Symptoms (PPS) vs. NCCP patients not meeting heart-related PPS criteria was evaluated on Clinical depression (PHQ-9 ≥ 10) (OR 5.22, p=<0.05). Non-cardiac chest pain patients meeting criteria for heart-related persistent physical symptoms were over five times more likely to experience clinical depression (OR 5.22) and had significantly more comorbid physical symptoms than those not meeting criteria.
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