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February 18, 2022Annals of Plastic Surgery6 citations

The Utility of the 5-Factor Modified Frailty Index to Predict Postoperative Risk in Microsurgical Reconstruction

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CMCarlos Eugenio MartínezAAAbdelaziz AtwezMDMartin Durkin

Key Result

The 5-factor modified frailty index predicts postoperative complications in microsurgical reconstruction, including an association between readmission and hypertension and COPD (P < 0.05).

Study Design

Type

Cohort (n=5,894)

Multicenter

Yes

Structured PICO

Does the 5-factor modified frailty index predict postoperative complications in microsurgical reconstruction patients?

P
Population
5,894 microsurgical reconstruction patients (2012-2016) from the American College of Surgeons National Quality Improvement Program base
I
Intervention
5-factor modified frailty index (5-mFI) assessment
C
Comparator
American Society of Anesthesiology (ASA) classification
O
Outcome
Postoperative complications

The 5-factor modified frailty index is a useful tool for predicting postoperative complications and identifying adjustable risks prior to microsurgical reconstruction.

Main Result

p-value: p=<0.05

Abstract

BACKGROUND: Microsurgical reconstruction is an integral part of plastic surgery. The 5-factor modified frailty index (5-mFI) is an effective tool to predict postoperative complications across multiple subspecialties. We aimed to determine if frailty scores using the 5-mFI can predict postoperative complications specifically in microvascular reconstruction. STUDY DESIGN: Frailty scores were retrospectively assessed in microsurgical reconstruction patients (2012-2016) using the American College of Surgeons National Quality Improvement Program base. The 5 variables that comprise the 5-mFI are history of chronic obstructive pulmonary disease, history of congestive heart failure, functional status, hypertension requiring medication and diabetes. The data were analyzed using the Goodman test, χ2 test, and a logistic regression model. The congruence was also compared between the 5-mFI and the American Society of Anesthesiology (ASA) classification in predicting complications. RESULTS: Of 5894 patients, the highest 5-mFI value was "3." Analyses show an increase in postoperative complications requiring ICU care. Further models indicate an association between readmission with hypertension and chronic obstructive pulmonary disease (P < 0.05). There was an increased risk of a failure to wean from ventilator with a history of chronic obstructive pulmonary disease and diabetes and an increased risk of readmission with a history of hypertension and chronic obstructive pulmonary disease. The 5-mFI and ASA were incongruent in predicting postoperative complications. CONCLUSIONS: The 5-mFI predicts postoperative complications in the microsurgical reconstruction population. Although the 5-mFI and ASA predict different complications, their use provides insight into the potential adjustable risks before surgery.

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Cite This Study

Martínez et al. (2022) conducted a cohort in Microsurgical reconstruction (n=5,894). 5-factor modified frailty index (5-mFI) vs. American Society of Anesthesiology (ASA) classification was evaluated on Postoperative complications (p=<0.05). The 5-factor modified frailty index predicts postoperative complications in microsurgical reconstruction, including an association between readmission and hypertension and COPD (P < 0.05).

synapsesocial.com/papers/6a0f2acb11edbd3546bdc6a7https://doi.org/10.1097/sap.0000000000003125
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