Key result
A dynamic linear approach applied to real ECG records from healthy subjects revealed that a relevant QTV fraction (over 40% in 19 of 23 segments) is not linearly driven by HRV.
Population
Simulated series, artificial ECG signals, and real ECG records from healthy subjects (23 segments analyzed)
Design
Other
Authors
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QTV independent of HRV may carry complementary information; hypothesis-generating in healthy subjects, prospective validation needed.
A significant portion of QT interval variability is not linearly driven by heart rate variability and may contain complementary clinical information.
Almeida et al. (2006) studied Healthy subjects. Dynamic linear autoregressive model was evaluated on Estimation of QTV fractions correlated and not correlated with HRV. A dynamic linear approach applied to real ECG records from healthy subjects revealed that a relevant QTV fraction (over 40% in 19 of 23 segments) is not linearly driven by HRV.
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