Key result
Poor medication and diet compliance accompanies ~39% of acute HF decompensations, followed by arrhythmias.
Why the study?
Few studies have examined the etiological aspects and precipitants of heart failure decompensation in the Nepalese population.
What are the major precipitating factors leading to decompensation of heart failure in patients with established heart failure?
Observational (n=101)
No
What are the major precipitating factors leading to decompensation of heart failure in patients with established heart failure?
Poor compliance and arrhythmias are the most common precipitating factors for acute decompensation of heart failure in a Nepalese tertiary care center, highlighting the need for patient education.
Supports targeting adherence in HF; leaves open generalizability beyond this single-center cohort.
Background and Aims: Heart failure is one of the debilitating conditions in patients with various forms of heart disease. It can have impacts on various aspects of the life of a patient. There have been few studies on the etiological aspects and precipitants of heart failure in the Nepalese population. The aim of our study is to find out the major factors that lead to decompensation of heart failure in patients who already have established heart failure. Methods: This study was a single-centre, prospective, observational study conducted in the emergency department of Manmohan Cardiothoracic Vascular and Transplant Centre (MCVTC) from 1st June 2019 to 30th November 2019. Hundred and one patients with established heart failure in the past, who presented again with decompensated heart failure were enrolled. Results: The mean age of the patients was 62.81 years (SD=15.92). Factors responsible for acute decompensation of heart failure were identified in 95.0 % of patients included in the study. The most common factor identified was poor compliance with medications and diet and fluid intake (38.6%). Next to it was arrhythmia identified in about 35.6% of cases.Other important factors responsible for decompensation in our study were infection (12.8%), anemia (4.9%) and ischemia (2.9%). Conclusion: Preventable and identifiable factors are responsible for the decompensation of heart failure. Most of these factors can be modified with the use of proper patient counseling/patient education, thereby reducing recurrent hospital admissions and economic burden to the patient and the government as well.
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Adhikari et al. (2020) conducted an observational in Decompensated heart failure (n=101). Poor compliance with medications and diet was the most common precipitating factor for acute decompensation of heart failure, identified in 38.6% of patients, followed by arrhythmia in 35.6%.
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