Key result
Atrial fibrillation was associated with increased ostial pulmonary vein diameter compared to non-AF controls (1.50 vs 1.20 cm, P<0.001), with further dilation observed in patients with hypertension.
Why the study?
Are atrial fibrillation and hypertension associated with increased ostial pulmonary vein diameter?
Population
100 patients with atrial fibrillation undergoing a pulmonary vein isolation procedure and 24 age- and…
Design
Case-control
Authors
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Supports PV stretch hypothesis in AF with hypertension; hypothesis-generating without practice implications.
Case-Control (n=124)
Are atrial fibrillation and hypertension associated with increased ostial pulmonary vein diameter?
Absolute Event Rate: 1.5% vs 1.2%
p-value: p=<0.001
Hypertension and atrial fibrillation are independently associated with increased ostial pulmonary vein diameter, supporting a stretch-induced mechanism for PV arrhythmias.
Herweg et al. (2005) conducted a case-control in Atrial fibrillation and hypertension (n=124). Atrial fibrillation vs. Non-AF controls was evaluated on Ostial PV diameter (cm) (p=<0.001). Atrial fibrillation was associated with increased ostial pulmonary vein diameter compared to non-AF controls (1.50 vs 1.20 cm, P<0.001), with further dilation observed in patients with hypertension.
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