Key result
Male and female ventricular repolarization patterns differ significantly, with men exhibiting higher J-point amplitudes and steeper ST segments, likely modulated by testosterone levels.
This review highlights significant gender differences in ventricular repolarization, likely driven by hormonal changes such as testosterone levels, which may explain the higher risk of drug-induced torsade de pointes in women.
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May refine sex-specific ECG norms; leaves open prospective validation of hormonal effects on arrhythmia risk.
Surawicz et al. (2003) conducted a review in Ventricular repolarization differences. Male gender vs. Female gender was evaluated. Male and female ventricular repolarization patterns differ significantly, with men exhibiting higher J-point amplitudes and steeper ST segments, likely modulated by testosterone levels.
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