Key result
SCORE2 models classify up to ~64% of individuals in four European countries as high CV risk.
Why the study?
The study aimed to characterize cardiovascular risk profiles across low-to-moderate mortality risk countries (Italy, Portugal, France, and Spain) using SCORE2 and SCORE2-OP models, while examining regional variations and healthcare professional involvement.
Observational (n=24,434)
Yes
A large proportion of individuals in low-to-moderate cardiovascular mortality risk countries are classified as high or very high risk using the SCORE2 and SCORE2-OP models, highlighting the need for targeted prevention.
Substantial high-risk classifications may warrant prevention focus; leaves open SCORE2 calibration in low-mortality regions.
Introduction: This study aims to characterize the cardiovascular risk profile in countries with low-to-moderate cardiovascular mortality risk (Italy, Portugal, France, and Spain) using the SCORE2 and SCORE2-OP models. It also examines regional variations and the involvement of healthcare professionals in performing risk assessments. Methods: A retrospective observational study was conducted using data from 24,434 cardiovascular risk assessments performed between December 2022 and July 2023 through a digital application used by physicians. The assessments used the SCORE2 model for individuals aged 40-69 and the SCORE2-OP model for those aged 70 and older. Risk stratification into "low-to-moderate," "high," and "very high" categories was analyzed based on individual risk factors such as age, smoking habits, systolic blood pressure, and cholesterol levels. Results: Approximately 50%-60% of individuals in these countries were classified as having "high" or "very high" cardiovascular risk. The highest proportions were observed in Portugal (62.44%) and Italy (64.05%), while lower proportions were found in Spain (46.65%) and France (52.74%). Regional analysis identified areas with the highest cardiovascular risk, such as Portalegre in Portugal and Apulia in Italy. Key risk factors included older age, smoking, high systolic blood pressure, and high non-HDL cholesterol. General practitioners were the primary healthcare professionals conducting these assessments. Discussion: The study highlights a significant proportion of individuals with "high" or "very high" cardiovascular risk in countries with low-to-moderate mortality risk. These findings underscore the need for targeted cardiovascular disease prevention strategies and the crucial role of general practitioners in managing cardiovascular risk.
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Fontainhas et al. (2024) conducted an observational in Cardiovascular risk (n=24,434). SCORE2 and SCORE2-OP models was evaluated on Proportion of individuals classified as having high or very high cardiovascular risk. Using the SCORE2 and SCORE2-OP models, 62.44% of individuals in Portugal, 64.05% in Italy, 46.65% in Spain, and 52.74% in France were classified as having high or very high cardiovascular risk.
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