April 26, 2013Circulation Arrhythmia and Electrophysiology
Outcome of Ventricular Tachycardia Ablation in Patients With Nonischemic Cardiomyopathy
Key result
Non-complete procedural success after ventricular tachycardia ablation in nonischemic cardiomyopathy was a strong predictor of VT recurrence (HR 8.20; 95% CI 2.37-28.43; P=0.001).
Why the study?
What are the outcomes and predictors of VT recurrence after ventricular tachycardia ablation in patients with nonischemic cardiomyopathy?
Population
45 patients with nonischemic cardiomyopathy accepted for ventricular tachycardia ablation, mean age 60±16…
Design
Cohort
Follow-up
25±15 months
Authors
Discussion
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Member takes
Implication
Supports targeting complete noninducibility during NICM VT ablation; leaves open randomized validation of procedural endpoints.
Study Design
Type
Cohort (n=45)
Structured PICO
What are the outcomes and predictors of VT recurrence after ventricular tachycardia ablation in patients with nonischemic cardiomyopathy?
P
Population
45 patients with nonischemic cardiomyopathy accepted for ventricular tachycardia (VT) ablation, mean age 60±16 years, left ventricular ejection fraction 44±14%.
I
Intervention
Ventricular tachycardia (VT) ablation, with epicardial mapping performed in 64% of patients.
O
Outcome
Ventricular tachycardia (VT) recurrence during follow-up.hard clinical
Main Result
Effect estimate: HR 8.20 (95% CI 2.37-28.43)
p-value: p=0.001
In patients with nonischemic cardiomyopathy undergoing VT ablation, complete procedural success (noninducibility of any monomorphic VT) is associated with low recurrence rates, whereas partial success or failure strongly predicts VT recurrence.
Cite This Study
Piers et al. (2013) conducted a cohort in Nonischemic cardiomyopathy with ventricular tachycardia (n=45). Ventricular tachycardia ablation vs. Complete procedural success vs. non-complete success was evaluated on Ventricular tachycardia recurrence (HR 8.20, 95% CI 2.37-28.43, p=0.001). Non-complete procedural success after ventricular tachycardia ablation in nonischemic cardiomyopathy was a strong predictor of VT recurrence (HR 8.20; 95% CI 2.37-28.43; P=0.001).