What question did this study set out to answer?

To describe the curation, structure, and computational tools of the MetaCyc metabolic pathway database and the BioCyc organism-specific pathway/genome database collection.

October 22, 2009Nucleic Acids ResearchOpen Access

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

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Authors

RCRon CaspiSRI International TATomer AltmanEP Analytics (United States)JDJoseph M. DaleSRI International

Discussion

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Implication

Database resource presents curated metabolic pathways and genome-wide networks across diverse organisms, highlighting tools for comparative genomics and multi-omics visualization.

Key Points

To describe the curation, structure, and computational tools of the MetaCyc metabolic pathway database and the BioCyc organism-specific pathway/genome database collection.
Curated experimentally verified small-molecule metabolic pathways and enzyme properties from primary scientific literature with supporting evidence codes and reviews.
Used Pathway Tools software with MetaCyc as a reference to predict metabolic networks, operons, transport systems, and missing pathway enzymes across sequenced genomes.
MetaCyc contains more than 1,400 curated metabolic pathways from all domains of life, representing the largest collection of experimentally validated pathways available.
BioCyc provides over 500 organism-specific Pathway/Genome Databases equipped with web-based comparative analysis tools and Omics Viewers for genome-scale data visualization.

Cite This Study

Caspi et al. (2009) studied this question.

synapsesocial.com/papers/6a0f66619e54838161fcaec3 https://doi.org/10.1093/nar/gkp875

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October 22, 2009Nucleic Acids ResearchOpen Access

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

View Full Paper

Ask AI

Bookmark

Authors

RCRon CaspiSRI International TATomer AltmanEP Analytics (United States)JDJoseph M. DaleSRI International

Discussion

Member takes

Implication

Database resource presents curated metabolic pathways and genome-wide networks across diverse organisms, highlighting tools for comparative genomics and multi-omics visualization.

Key Points

To describe the curation, structure, and computational tools of the MetaCyc metabolic pathway database and the BioCyc organism-specific pathway/genome database collection.
Curated experimentally verified small-molecule metabolic pathways and enzyme properties from primary scientific literature with supporting evidence codes and reviews.
Used Pathway Tools software with MetaCyc as a reference to predict metabolic networks, operons, transport systems, and missing pathway enzymes across sequenced genomes.
MetaCyc contains more than 1,400 curated metabolic pathways from all domains of life, representing the largest collection of experimentally validated pathways available.
BioCyc provides over 500 organism-specific Pathway/Genome Databases equipped with web-based comparative analysis tools and Omics Viewers for genome-scale data visualization.

Cite This Study

Caspi et al. (2009) studied this question.

synapsesocial.com/papers/6a0f66619e54838161fcaec3 https://doi.org/10.1093/nar/gkp875

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