Key result
Multimodality tissue tracking (MTT) quantified right ventricular peak global longitudinal strain correlated closely with strain-encoding MRI (r = 0.72, p < 0.001).
Why the study?
Does multimodality tissue tracking (MTT) accurately measure bi-ventricular strain compared to SENC and HARP MRI in patients with pulmonary hypertension?
Observational (n=45)
Does multimodality tissue tracking (MTT) accurately measure bi-ventricular strain compared to SENC and HARP MRI in patients with pulmonary hypertension?
Multimodality tissue tracking provides a valid method for measuring right ventricular longitudinal strain in pulmonary hypertension patients, correlating well with strain-encoding MRI.
Supports MTT for RV strain in PH; leaves open prospective validation before clinical adoption.
article i nfo Background:Pixel-basedmultimodality tissuetracking (MTT) isa newnoninvasivemethodfor thequantification of cardiac deformation from cine image of MRI. The aim of this study is to validate bi-ventricular strain measure- ment by MTT compared to strain-encoding (SENC) MRI and harmonic phase (HARP) MRI in pulmonary hyper- tension (PH) patients. Methods:In 45 subjects (30 PH patients and 15 normal subjects), RV and LV peak global longitudinal strains (Ell) were measured from long axis 4 chamber view using MTT. LV peak global circumferential strains (Ecc) by MTT were measured from short axis. For validation, RV and LV Ell by MTT were compared to measures by SENC- MRI from short axis, and LV Ecc by MTT was compared to measures by short axis tagged MRI analysis (HARP). Reproducibility of MTT was also determined. Results: MTT quantified RV Ell correlated closelyto those of SENC (r = 0.72, p b 0.001), with good limits of agree- ment.LVEllquantifiedbyMTTshowedmoderatecorrelationwithSENC(r=0.57,p=0.001),andLVEccbyMTT
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Ohyama et al. (2014) conducted an observational in Pulmonary Hypertension (n=45). Multimodality tissue tracking (MTT) vs. Strain-encoding (SENC) MRI and harmonic phase (HARP) MRI was evaluated on Correlation of right ventricular peak global longitudinal strain (Ell) between MTT and SENC (r = 0.72, p=<0.001). Multimodality tissue tracking (MTT) quantified right ventricular peak global longitudinal strain correlated closely with strain-encoding MRI (r = 0.72, p < 0.001).
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