Key result
Exercise cardiac magnetic resonance imaging revealed significantly lower resting right ventricular longitudinal strain in PAH patients compared to controls (-16.6 vs -20.1, P=0.03).
Why the study?
Does exercise cardiac magnetic resonance feature tracking detect subclinical right ventricular dysfunction and ventriculo-ventricular interaction in patients with pulmonary arterial hypertension?
Population
9 subjects with pulmonary arterial hypertension (PAH) and 9 control subjects
Comparison
Cardiac magnetic resonance feature tracking at… vs Control subjects
Design
Cohort
Authors
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Supports cMRI-FT detection of subclinical RV dysfunction in PAH with normal RVEF; hypothesis-generating for ventriculo-ventricular interaction assessment.
Observational (n=18)
Does exercise cardiac magnetic resonance feature tracking detect subclinical right ventricular dysfunction and ventriculo-ventricular interaction in patients with pulmonary arterial hypertension?
Absolute Event Rate: -16.6% vs -20.1%
p-value: p=0.03
Exercise cMRI-FT can detect subclinical right ventricular dysfunction and impaired contractile reserve in PAH patients who have a normal resting ejection fraction.
Lin et al. (2018) conducted an observational in Pulmonary arterial hypertension (n=18). Exercise cardiac magnetic resonance imaging with myocardial feature tracking vs. Healthy controls was evaluated on Right ventricular longitudinal strain (Ell RV) at rest (p=0.03). Exercise cardiac magnetic resonance imaging revealed significantly lower resting right ventricular longitudinal strain in PAH patients compared to controls (-16.6 vs -20.1, P=0.03).
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