Key result
Otsu-Auto-Threshold (OAT) quantification accurately measured late gadolinium enhancement mass in acute MI (26.1 g vs 25.4 g for 5SD; P=0.088) and acute myocarditis with high reproducibility.
Why the study?
Does the Otsu-Auto-Threshold method accurately and reproducibly quantify late gadolinium enhancement in patients with acute heart disease compared to standard thresholding methods?
Population
58 patients with acute heart disease (28 with acute myocardial infarction and 30 with acute myocarditis)
Comparison
Otsu-Auto-Threshold method for late gadolinium… vs Thresholds using 2 standard deviations, 3SD, and…
Design
Cross-sectional, blinded visual assessment
Authors
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OAT may enable user-independent LGE quantification in acute settings; leaves open prospective validation before clinical adoption.
Observational (n=58)
Blinded
Does the Otsu-Auto-Threshold method accurately and reproducibly quantify late gadolinium enhancement in patients with acute heart disease compared to standard thresholding methods?
Absolute Event Rate: 26.1% vs 25.4%
p-value: p=0.088
The Otsu-Auto-Threshold method is an accurate and reproducible user-independent technique for quantifying late gadolinium enhancement in acute myocardial infarction and myocarditis.
Vermès et al. (2012) conducted an observational in Acute heart disease (acute myocardial infarction and acute myocarditis) (n=58). Otsu-Auto-Threshold (OAT) vs. 2SD, 3SD, 5SD, FWHM, and visual assessment was evaluated on Late gadolinium enhancement (LGE) mass (p=0.088). Otsu-Auto-Threshold (OAT) quantification accurately measured late gadolinium enhancement mass in acute MI (26.1 g vs 25.4 g for 5SD; P=0.088) and acute myocarditis with high reproducibility.
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