Key result
Whole-genome phylogenetic analysis of 12 newly sequenced human rhinovirus genomes reveals that HRV-B and human enteroviruses diverged from a common ancestor after their separation from HRV-A.
Population
12 HRV-A and HRV-B serotypes
Comparison
Whole-genome maximum-likelihood phylogenetic… vs Human enteroviruses (HEV)
Design
Preclinical
Authors
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Refines HRV evolutionary relationships; leaves open functional validation and clinical translation.
Complete genome sequencing of 12 HRV serotypes reveals phylogenetic relationships and genomic differences between HRV-A, HRV-B, and human enteroviruses.
Tapparel et al. (2007) studied Human rhinovirus (n=34). Whole-genome phylogenetic analysis of 12 newly sequenced human rhinovirus genomes reveals that HRV-B and human enteroviruses diverged from a common ancestor after their separation from HRV-A.