Key result
TMR index ≥0.040 is linked to ~227% higher SCD risk in chronic heart failure.
Why the study?
Does the T-wave morphology restitution (TMR) index predict sudden cardiac death in ambulatory patients with chronic heart failure?
Population
651 ambulatory patients with chronic heart failure from the MUSIC study
Comparison
T-wave morphology restitution index ≥0.040… vs TMR <0.040
Design
Cohort
Authors
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May support TMR for SCD risk stratification in chronic HF; leaves open incremental value over standard markers pending validation.
Observational (n=651)
Does the T-wave morphology restitution (TMR) index predict sudden cardiac death in ambulatory patients with chronic heart failure?
Effect estimate: HR 3.27
p-value: p=<0.001
T-wave morphology restitution (TMR) derived from Holter ECG is a strong, independent predictor of sudden cardiac death in patients with chronic heart failure.
Ramírez et al. (2017) conducted an observational in chronic heart failure (n=651). T-wave morphology restitution (TMR) ≥0.040 vs. TMR <0.040 was evaluated on Sudden cardiac death (SCD) (HR 3.27, p=<0.001). A T-wave morphology restitution (TMR) index ≥0.040 was strongly associated with sudden cardiac death in patients with chronic heart failure (HR 3.27; P<0.001).
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