Key result
Clinical trials over the past three decades have fundamentally shifted arrhythmia management, demonstrating that some antiarrhythmic therapies may increase mortality and guiding the use of specific agents.
Population
Patients with arrhythmias, including postinfarct patients with ventricular ectopy, patients with ventricular…
Design
Review
Authors
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Refines antiarrhythmic selection in practice; leaves open optimal integration with contemporary devices and ablation.
This review highlights the critical role of clinical trials in shifting arrhythmia management away from indiscriminate suppression of ectopy toward targeted therapies and the use of class II/III agents or ICDs.
James A. Reiffel (1996) conducted a review in Arrhythmias. Antiarrhythmic therapy was evaluated. Clinical trials over the past three decades have fundamentally shifted arrhythmia management, demonstrating that some antiarrhythmic therapies may increase mortality and guiding the use of specific agents.
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