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October 1, 2000Journal of Cardiovascular Electrophysiology

Laplacian Electrograms and the Interpretation of Complex Ventricular Activation Patterns During Ventricular Fibrillation

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Why the study?

Does the use of Laplacian electrograms improve the detection of local activation during ventricular fibrillation in isolated porcine hearts?

Population

Isolated perfused porcine intact hearts

Comparison

Laplacian electrograms calculated from local… vs Standard local unipolar electrograms

Design

Preclinical

Authors

RCRuben CoronelFWF.J.G. Wilms-SchopmanJGJoris R. de Groot

Discussion

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Overview

Laplacian electrograms may aid local activation detection in VF; leaves open translation to human mapping and defibrillation outcomes.

Structured PICO

Does the use of Laplacian electrograms improve the detection of local activation during ventricular fibrillation in isolated porcine hearts?

P
Population
Isolated perfused porcine intact hearts
I
Intervention
Laplacian electrograms calculated from local unipolar electrograms (13 x 19 matrix, interelectrode distance 0.3 mm)
C
Comparator
Standard local unipolar electrograms
O
Outcome
Detection of the moment of local activation without interference from remote activity or repolarization wavessurrogate

Laplacian electrograms allow accurate detection of local activation during complex arrhythmias like VF without interference from remote activity, potentially optimizing defibrillation success.

Cite This Study

Coronel et al. (2000) studied this question.

synapsesocial.com/papers/6a0f8c5ab6f5ee04015fcb87https://doi.org/10.1111/j.1540-8167.2000.tb01758.x
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