Key result
Epidemiological nomogram predicts long-term CVD mortality in multiple myeloma survivors with a ~0.73 C-index.
Why the study?
Survival of multiple myeloma patients has significantly improved and several factors increase the risk of cardiovascular death, but the prognostic significance of factors associated with long-term CVD risk in MM survivors required determination.
Population
Multiple myeloma survivors surviving longer than 36 months in the SEER database between 2000 and 2015
Design
Retrospective database cohort study with propensity score matching
Authors
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Offers a potential cardio-oncology risk stratification tool; leaves open whether implementing.
Cohort
Effect estimate: C-index 0.726
A nomogram based on epidemiological variables can accurately predict 5-, 10-, and 15-year cardiovascular mortality risk in multiple myeloma survivors.
Chen et al. (2023) conducted a cohort in Multiple myeloma. Nomogram based on epidemiological variables was evaluated on Cardiovascular death probabilities (C-index 0.726). A nomogram based on epidemiological variables accurately predicted 5-, 10-, and 15-year cardiovascular disease mortality in multiple myeloma survivors (validation C-index 0.726).
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