Key result
Targeted nutritional and immunomodulatory therapy improves LVEF to 56% in post-gastric bypass fulminant myocarditis.
Case Report (n=1)
No
Severe post-bariatric malnutrition can trigger fulminant myocarditis and cardiovascular collapse, highlighting the critical need for vigilant long-term nutritional follow-up after bariatric surgery.
Answers are grounded in this paper and cite their sources.
May support LVEF recovery in post-bariatric myocarditis; single case leaves open causality and generalizability.
Fulminant myocarditis (FM) is a rare, life-threatening inflammatory disease of the myocardium characterized by sudden, severe cardiac dysfunction and hemodynamic instability. It often necessitates high-dose inotropic support and mechanical circulatory assistance, with a high risk of short-term mortality. We describe a 23-year-old woman who developed FM 18 months after undergoing Roux-en-Y gastric bypass. She presented with cardiogenic shock and ventricular arrhythmias precipitated by a period of clinical non-adherence and discontinued nutritional supplementation. Infectious and autoimmune workups were negative, but profound micronutrient and trace element deficiencies were identified. Emergency management included mechanical ventilation, inotropes, immunomodulatory therapy, and aggressive nutritional repletion. Cardiac magnetic resonance imaging confirmed myocarditis. Over two months, her left ventricular ejection fraction improved from approximately 25% to 56%, accompanied by full clinical recovery. This case illustrates the potential role of severe post-bariatric malnutrition in triggering myocardial inflammation and cardiovascular collapse. It underscores the importance of early recognition, multidisciplinary management, including immunomodulatory and nutritional therapy, and the necessity of vigilant long-term follow-up in patients after bariatric surgery to prevent such catastrophic outcomes.
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Kopaleishvili et al. (2026) conducted a case report in Fulminant myocarditis (n=1). Targeted nutritional repletion and immunomodulatory therapy was evaluated on Left ventricular ejection fraction (LVEF). Targeted nutritional repletion and immunomodulatory therapy improved left ventricular ejection fraction from 25% to 56% in a 23-year-old woman with fulminant myocarditis post-gastric bypass.
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