Key result
Loci on murine chromosome 6 and possibly chromosome 1 regulate susceptibility to experimental autoimmune myocarditis and T cell apoptosis in A.SW mice, overlapping with diabetes loci in NOD mice.
Authors
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Hypothesis-generating for shared autoimmune genetic risk; leaves open human translation and therapeutic targeting.
Güler et al. (2005) studied Experimental autoimmune myocarditis. Genetic loci on murine chromosome 6 and 1 was evaluated on Susceptibility to experimental autoimmune myocarditis and apoptosis regulation. Loci on murine chromosome 6 and possibly chromosome 1 regulate susceptibility to experimental autoimmune myocarditis and T cell apoptosis in A.SW mice, overlapping with diabetes loci in NOD mice.
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