Key result
Consuming under one alcoholic drink daily is not linked to altered stroke risk in AF.
Why the study?
Little was known about the association between alcohol consumption and risk of cardiovascular events in patients with established AF.
Does regular alcohol intake affect the risk of stroke or systemic embolism in patients with established atrial fibrillation?
Cohort (n=3,852)
Yes
Does regular alcohol intake affect the risk of stroke or systemic embolism in patients with established atrial fibrillation?
Effect estimate: HR 0.87 (95% CI 0.55-1.37)
Absolute Event Rate: 0.9% vs 1.29%
p-value: p=0.71 for linear trend
Low to moderate alcohol intake is not significantly associated with an increased risk of stroke, systemic embolism, or bleeding in patients with established atrial fibrillation.
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Low alcohol intake showed no significant thromboembolic association in AF; leaves open questions on causality and higher intakes.
Reddiess et al. (2021) conducted a cohort in Established atrial fibrillation (n=3,852). Alcohol consumption vs. Nondrinkers was evaluated on Composite of stroke and systemic embolism (HR 0.87, 95% CI 0.55-1.37, p=0.71 for linear trend). In patients with established atrial fibrillation, consuming >0 to <1 alcoholic drink per day did not significantly alter the risk of stroke or systemic embolism compared to nondrinkers (HR 0.87).
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