Key result
A method of coronary occlusion was developed to induce experimental myocardial infarction in small animals.
Facilitates reproducible MI models in small animals for preclinical testing; extends translational research beyond large-animal requirements.
Bethesda, Maryland THE CLINIC OF SURGERY, NATIONAL HEART INSTITUTE, AND THE LABORATORY DISEASES, NATIONAL MICRO-BIOLOGICAL INSTITUTE, NATIONAL INSTITUTES OF HEALTH, UNITED STATES PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH, EDUCATION AND WELFARE, BETHESDA, MARYLAND
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Johns et al. (1954) studied this question. A method of coronary occlusion was developed to induce experimental myocardial infarction in small animals.
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