Key result
Catheter ablation as first-line therapy for atrial fibrillation was associated with a higher long-term multiple procedure success rate compared to ablation after AAD failure (78% vs. 64%, P=0.03).
Why the study?
Does catheter ablation as first-line therapy improve long-term success rates compared to ablation after antiarrhythmic drug failure in patients with atrial fibrillation?
Cohort (n=434)
No
Does catheter ablation as first-line therapy improve long-term success rates compared to ablation after antiarrhythmic drug failure in patients with atrial fibrillation?
Absolute Event Rate: 78% vs 64%
p-value: p=0.03
Catheter ablation as first-line therapy for atrial fibrillation is associated with a higher long-term success rate and fewer repeat procedures compared to ablation after antiarrhythmic drug failure.
No takes yet. Share an insight, caveat, or question.
Observational data should not yet shift ablation timing in AF; leaves open need for RCTs to confirm long-term benefit.
Tanner et al. (2011) conducted a cohort in Atrial fibrillation (n=434). Catheter ablation as first-line therapy vs. Catheter ablation after antiarrhythmic drug failure was evaluated on Long-term multiple procedure success rate (p=0.03). Catheter ablation as first-line therapy for atrial fibrillation was associated with a higher long-term multiple procedure success rate compared to ablation after AAD failure (78% vs. 64%, P=0.03).
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