Why the study?
The study aimed to detect early retinal vascular changes using OCTA in T1DM patients without diabetic retinopathy and evaluate their correlation with carotid intima-media thickness.
Do patients with type 1 diabetes mellitus without diabetic retinopathy exhibit early retinal microvascular changes that correlate with increased carotid intima-media thickness compared to healthy controls?
Population
38 adult patients with T1DM without diabetic retinopathy and 38 matched healthy controls
Comparison
T1DM patients without diabetic retinopathy vs healthy controls
Design
Case-control and cross-sectional study
Authors
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May support OCTA for detecting early microvascular changes in T1DM without DR; hypothesis-generating for carotid IMT links.
Do patients with type 1 diabetes mellitus without diabetic retinopathy exhibit early retinal microvascular changes that correlate with increased carotid intima-media thickness compared to healthy controls?
Optical coherence tomography angiography can detect early microvascular changes in patients with type 1 diabetes without diabetic retinopathy, which correlate with increased carotid intima-media thickness.
Ulutaş et al. (2021) studied this question.